Best known as the first woman to own a seat on the New York Stock Exchange and the first to head one of its member firms, Muriel F. “Mickie” Siebert died of complications from cancer on August 24 at the age of 80.

She was the founder, chairwoman and CEO of Siebert Financial Corporation and its wholly owned subsidiary, Muriel Siebert & Co., Inc.

Joseph M. Ramos, the company’s Chief Operating Officer, as principal executive officer, will continue handling the functions performed by Siebert.

She was also a pioneer in the discount brokerage field, transforming her firm into a discount brokerage in 1975—the first day NYSE members were allowed to negotiate commissions. In 1977, she put her firm in a blind trust to serve as New York State’s first woman Superintendent of Banking—a position she held for five years.

Siebert continually championed the rights of women and individual investors. She was also a strong advocate for sound business practices in the industry, writing opinion pieces for major media outlets, testifying before Congress and frequently quoted in the press. U.S. Banker Magazine named her one of the “25 Most Powerful Women in Finance” as recently as 2010.

She founded the “Siebert Personal Finance Program: Taking Control of Your Financial Future,” which was created to teach basic financial skills to middle and high school students and adults.

“This is obviously a great loss not only for our company but for the financial industry in general, “said Ramos in a statement. “Mickie was a pioneer and recognized as a leader throughout the industry and beyond. She was respected as a strong voice of integrity, reason and sound business practices. Although she is best known as the first woman to own a seat on the NYSE, she really became one of the great personalities on Wall Street of either sex. Those of us who worked with her will miss her spirit, leadership and great commitment to her clients and the securities markets. We will work to continue her legacy.”

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